Supplements

Pre-Workout Guide: Ingredients, Caffeine and How to Use It

What's in it, how to use it, and how to pick your level.

Muscle Nation •4 min read •01 Sep 2026
Key takeaways
  • Pre-workout gives you energy, focus and pump for harder training.
  • Caffeine is the main driver, so start low if you're new to it.
  • Muscle Nation has three levels, from high-stim to caffeine-free.
  • Take it around 20-30 minutes before you train.

We’ve all had that session we nearly talked ourselves out of. Pre-workout is for exactly those days. The tricky part is the label. Different caffeine levels, stim and caffeine-free formulas, and a row of ingredient names most people have never heard of. This guide explains what’s actually in pre-workout, what each ingredient does, and how to pick the right one for you.

What pre-workout is

Pre-workout is a supplement, usually a powder you mix with water and drink before training. It’s there to support your energy, focus, endurance and pump. Most formulas pair a stimulant (almost always caffeine) with performance ingredients like amino acids and nitric-oxide boosters. The idea is simple: help you show up sharper and get more out of the session.

What’s in it, and what each bit does

Pre-workout labels can read like a chemistry exam. These are the ingredients worth knowing.

Caffeine is the one you feel. It supports energy, alertness and focus, and can make a hard session feel a touch easier. Doses vary a lot between products, which is the main thing to pay attention to. L-Citrulline supports blood flow and that pump feeling by helping your body produce nitric oxide. Glycerol, which you’ll see as Glycersize, pulls water into your blood and muscle for fuller pumps and better hydration. Agmatine (Agmapure on the label) works alongside citrulline to keep those pumps going. Carnitine is an amino acid involved in energy metabolism that some formulas add. And beta-alanine helps buffer your muscles during higher-rep work. It’s also the ingredient behind the harmless skin-tingle some pre-workouts give you, though not every formula includes it.

You don’t need a label crammed with every ingredient under the sun. You need sensible doses of the ones that count, on a panel you can actually read.

Our pre-workout range: pick your level

The easiest way to choose is by how much caffeine you want and when you train. We make three.

IMMORTAL is the high-stim one, with 400mg of caffeine and clinical doses across the board, built for serious lifters chasing maximum energy and focus. It’s strong, so start with half a serve to see how you handle it, and keep it to earlier in the day. It comes in 40 serves.

DESTINY Shred is the smoother, everyday option. It has a sensible 150mg of caffeine plus 2,000mg of carnitine and a 13-ingredient formula, with no heavy stimulants, no jitters and no tingles. It’s also gluten free and vegan friendly. If you’re new to pre-workout or sit on the sensitive side, this is the one to start with. It comes in 30 serves.

PUMP is caffeine-free, built purely for performance and pumps. It packs 8,000mg of L-Citrulline, 2,000mg of Glycersize and 1,000mg of Agmapure, with no caffeine at all. Use it for evening sessions so it won’t touch your sleep, if you’re caffeine-sensitive, or stacked with a stim pre-workout when you want bigger pumps. It comes in 40 serves.

Browse all three in Pre-Workouts.

How much caffeine should a beginner have?

Start low. Around 150 to 200mg of caffeine gives most people a noticeable lift without the jitters or the crash, which is why DESTINY at 150mg is a friendlier place to start than a high-stim formula. If you go straight to something like IMMORTAL at 400mg, take half a serve first and see how you respond. Piling on more caffeine doesn’t get you a better workout. It just gets you more wired.

How and when to take it

Mix your pre-workout with water and drink it about 30 to 45 minutes before you train, so the ingredients have time to kick in. If you’re new or caffeine-sensitive, start with half a serve and build from there. Drink plenty of water around your session, especially with a stim pre. And if you train at night, switch to a caffeine-free option like PUMP so it doesn’t wreck your sleep, or save your stim pre for earlier in the day.

How to choose the right one

Match it to when you train first. A high-stim pre suits mornings, while a caffeine-free one is better at night. Then be honest about your caffeine tolerance. IMMORTAL at 400mg is for experienced users, DESTINY at 150mg is the gentler everyday pick, and PUMP has none. Decide whether you’re after stim, pump, or both. You can run PUMP on its own in the evening, or stack it with a stim pre for the best of both. After that, pick a flavour you’ll look forward to, because that’s half the battle with staying consistent.

A few quick tips

If you feel a tingle, that’s beta-alanine, and it’s harmless. Not every formula has it, and DESTINY doesn’t. Keep an eye on your total caffeine for the day, especially with IMMORTAL, since your coffees count too. And if you notice a pre-workout losing its kick, take a short break to let your tolerance reset.

DESTINY Pre-Workout Burn

30 Servings - Peach Rings

Regular price $59.99

DESTINY Pre-Workout Burn

30 Servings - Peach Iced Tea

Regular price $59.99

IMMORTAL Pre-Workout

40 Servings - Red Zone

Regular price $74.99

IMMORTAL Pre-Workout

40 Servings - Tropical

Regular price $74.99

IMMORTAL Pre-Workout

40 Servings - Blue Raspberry

Regular price $74.99

IMMORTAL Pre-Workout

40 Servings - Mango Passionfruit

Regular price $74.99

PUMP Pre-Workout Caffeine Free

40 Servings - Mango

Regular price $74.99

PUMP Pre-Workout Caffeine Free

40 Servings - Pineapple

Regular price $74.99

Frequently asked questions

What does pre-workout do? It supports your energy, focus, endurance and pump before training, through caffeine and performance ingredients like citrulline and glycerol.

When should I take pre-workout? About 30 to 45 minutes before you train, mixed with water.

Which pre-workout is best for beginners? Start with a moderate-caffeine option like DESTINY at 150mg and see how you feel before moving up to a high-stim formula like IMMORTAL at 400mg.

Can I take pre-workout at night? Yes, if you choose a caffeine-free one like PUMP so it doesn’t affect your sleep.

Can I mix two pre-workouts? A common combo is stacking a caffeine-free pump formula like PUMP with a stim pre. Just keep your total caffeine sensible.

Ready to train

Pre-workout is a simple way to show up with more in the tank, once you know what’s in it. Match the formula to your training time and your caffeine tolerance. IMMORTAL for serious energy, DESTINY for an everyday hit, PUMP for caffeine-free pumps.

Shop pre-workout →

This is general information, not personal health advice. Pre-workouts contain caffeine, and IMMORTAL is high-stim at 400mg, so they aren’t suitable for everyone. If you’re pregnant, sensitive to caffeine, or have a health condition, speak with a qualified health professional first.